About 50% of patients that use isotretinoin never need to do anything else for acne.

In the first few weeks of using isotretinoin, roughly one in five patients will see their acne condition get a little worse. Every 1/500 patients see their acne condition get much worse. For the rest of the patients, their condition either get much better or better for a while.

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Why Isotretinoin is Safe and Encouraged for Severe Acne Treatment

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